Genetic variants in the transcription regulatory region of MEGF10 are associated with autism in Chinese Han population

Genetic variants in the transcription regulatory region of MEGF10 are associated with autism in Chinese Han population

Abstract Multiple epidermal growth factor-like-domains 10 (MEGF10), a critical member of the apoptotic engulfment pathway, mediates axon pruning and synapse elimination during brain development. Previous studies indicated that synaptic pruning deficit was associated with autism-related phenotypes. H...

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Bibliographic Details
Main Authors: Zhiliu Wu, Jian Qin, Yang You, Yuanlin Ma, Meixiang Jia, Linyan Wang, Tianlan Lu, Weihua Yue, Yanyan Ruan, Dai Zhang, Jun Li, Lifang Wang
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02348-1

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https://doi.org/10.1038/s41598-017-02348-1

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