The GnRH receptor and the response of gonadotrope cells to GnRH pulse frequency code. A story of an atypical adaptation of cell function relying on a lack of receptor homologous desensitization.

Brain control of the reproductive system is mediated through hypothalamic gonadotropin-releasing hormone (GnRH) which activates specific receptors (GnRHR) present at the surface of the pituitary gonadotropes to trigger secretion of the two gonadotropins LH and FSH. A unique feature of this system is...

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Bibliographic Details
Main Authors: Christian Bleux, Violaine Simon, Jean-NoĂŤl Laverriere, Ghislaine Garrel, Raymond Counis, Solange Magre, JoĂŤlle Cohen-Tannoudji
Format: Article
Language:English
Published: Via Medica 2010-01-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4285