A FABP4-PPARγ signaling axis regulates human monocyte responses to electrophilic fatty acid nitroalkenes

A FABP4-PPARγ signaling axis regulates human monocyte responses to electrophilic fatty acid nitroalkenes

Nitro-fatty acids (NO2-FA) are electrophilic lipid mediators derived from unsaturated fatty acid nitration. These species are produced endogenously by metabolic and inflammatory reactions and mediate anti-oxidative and anti-inflammatory responses. NO2-FA have been postulated as partial agonists of t...

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Main Authors: M. Lamas Bervejillo, J. Bonanata, G.R. Franchini, A. Richeri, J.M. Marqués, B.A. Freeman, F.J. Schopfer, E.L. Coitiño, B. Córsico, H. Rubbo, A.M. Ferreira
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719308523

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http://www.sciencedirect.com/science/article/pii/S2213231719308523

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