PMS2 gene mutation results in DNA mismatch repair system failure in a case of adult granulosa cell tumor
Abstract Background Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecular studies have characterized the FOXL2 402C > G mutation in adult...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-03-01
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Series: | Journal of Ovarian Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13048-017-0317-4 |