Investigating <i>LMNA</i>-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Investigating <i>LMNA</i>-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

<i>LMNA</i>-related dilated cardiomyopathy is an inherited heart disease caused by mutations in the <i>LMNA</i> gene encoding for lamin A/C. The disease is characterized by left ventricular enlargement and impaired systolic function associated with conduction defects and vent...

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Bibliographic Details
Main Authors: Yuval Shemer, Lucy N. Mekies, Ronen Ben Jehuda, Polina Baskin, Rita Shulman, Binyamin Eisen, Danielle Regev, Eloisa Arbustini, Brenda Gerull, Mihaela Gherghiceanu, Eyal Gottlieb, Michael Arad, Ofer Binah
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>LMNA</i>
dilated cardiomyopathy
iPSC-CMs
electrophysiology
arrhythmia
Online Access:https://www.mdpi.com/1422-0067/22/15/7874

Internet

https://www.mdpi.com/1422-0067/22/15/7874

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