Lipoarabinomannan in Active and Passive Protection Against Tuberculosis

Glycolipids of the cell wall of Mycobacterium tuberculosis (Mtb) are important immunomodulators in tuberculosis. In particular, lipoarabinomannan (LAM) has a profound effect on the innate immune response. LAM and its structural variants can be recognized by and activate human CD1b-restricted T cells...

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Bibliographic Details
Main Authors: Margarida Correia-Neves, Christopher Sundling, Andrea Cooper, Gunilla Källenius
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01968/full