The changing paradigm: estrogen receptor α recognition on DNA and within the dynamic nature of nucleosomes

Estrogen receptor alpha (ERα) plays a major role in the expression of estrogen-responsive genes. Although its conventional binding characteristics have been considered coincident with & exclusively in the class of steroid hormone receptors, increasing evidence challenges this paradigm. ERα was s...

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Bibliographic Details
Main Authors: William M. Scovell, Sachindra R. Joshi
Format: Article
Language:English
Published: AIMS Press 2015-03-01
Series:AIMS Molecular Science
Subjects:
Online Access:http://www.aimspress.com/article/10.3934/molsci.2015.2.48/fulltext.html