Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria.

Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria.

Plasmodium falciparum PfRH5 protein binds Ripr, CyRPA and Pf113 to form a complex that is essential for merozoite invasion of erythrocytes. The inter-genomic conservation of the PfRH5 complex proteins makes them attractive blood stage vaccine candidates. However, little is known about how antibodies...

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Bibliographic Details
Main Authors: Frederica D Partey, Filip C Castberg, Edem W Sarbah, Sarah E Silk, Gordon A Awandare, Simon J Draper, Nicholas Opoku, Margaret Kweku, Michael F Ofori, Lars Hviid, Lea Barfod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5993283?pdf=render

Internet

http://europepmc.org/articles/PMC5993283?pdf=render

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