Characterization of Neoantigen Load Subgroups in Gynecologic and Breast Cancers

Characterization of Neoantigen Load Subgroups in Gynecologic and Breast Cancers

ObjectiveAlthough gynecologic and breast (Pan-Gyn) cancers share a variety of similar characteristics, their response to immunotherapy is different. Immune checkpoint inhibitor therapy is not effective in all patients, while neoantigen load (NAL) may be a predictive biomarker. However, the selection...

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Bibliographic Details
Main Authors: Yue Zhu, Xiaowei Meng, Xinjia Ruan, Xiaofan Lu, Fangrong Yan, Fei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
gynecologic and breast cancer
neoantigen load
immune infiltrate
intratumor heterogeneity
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00702/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00702/full

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