Direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors

The direct lineage reprogramming of somatic cells to other lineages by defined factors has led to innovative cell-fate-change approaches for providing patient-specific cells. Recent reports have demonstrated that four pluripotency factors (Oct4, Sox2, Klf4, and c-Myc) are sufficient to directly repr...

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Bibliographic Details
Main Authors: Han-Seop Kim, Janghwan Kim, Yeonju Jo, Daejong Jeon, Yee Sook Cho
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506113001335