Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data

<p>Abstract</p> <p>Background</p> <p>Calcium (Ca2+) handling proteins are known to play a pivotal role in the pathophysiology of cardiomyopathy. However little is known about early changes in the diabetic heart and the impact of insulin treatment (Ins).</p> <p&...

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Bibliographic Details
Main Authors: Fredersdorf Sabine, Thumann Christian, Zimmermann Wolfram H, Vetter Roland, Graf Tobias, Luchner Andreas, Riegger Günter AJ, Schunkert Heribert, Eschenhagen Thomas, Weil Joachim
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://www.cardiab.com/content/11/1/57