Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system
The gut microbiota may contribute to depression, but the underlying mechanism is not well understood. Here the authors use a mouse model of stress induced depression to demonstrate that behavioural changes conferred by fecal transplant from stressed to naïve mice require the endocannabinoid system.
Main Authors: | Grégoire Chevalier, Eleni Siopi, Laure Guenin-Macé, Maud Pascal, Thomas Laval, Aline Rifflet, Ivo Gomperts Boneca, Caroline Demangel, Benoit Colsch, Alain Pruvost, Emeline Chu-Van, Aurélie Messager, François Leulier, Gabriel Lepousez, Gérard Eberl, Pierre-Marie Lledo |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-12-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-19931-2 |
Similar Items
-
Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system.
by: Emma Colucci-Guyon, et al.
Published: (2020-12-01) -
Changes in Gut Microbiota by Chronic Stress Impair the Efficacy of Fluoxetine
by: Eleni Siopi, et al.
Published: (2020-03-01) -
Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring.
by: Fred S Sarfo, et al.
Published: (2011-07-01) -
L'activation des α-sécrétases : une nouvelle stratégie thérapeutique pour le traitement du traumatisme crânien
by: Siopi, Eleni
Published: (2012) -
L'activation des α-sécrétases : une nouvelle stratégie thérapeutique pour le traitement du traumatisme crânien
by: Siopi, Eleni
Published: (2012)