Young and Especially Senescent Endothelial Microvesicles Produce NADPH: The Fuel for Their Antioxidant Machinery
In a previous study, we demonstrated that endothelial microvesicles (eMVs) have a well-developed enzymatic team involved in reactive oxygen species detoxification. In the present paper, we demonstrate that eMVs can synthesize the reducing power (NAD(P)H) that nourishes this enzymatic team, especiall...
Main Authors: | Guillermo Bodega, Matilde Alique, Lourdes Bohórquez, Miriam Morán, Luis Magro, Lilian Puebla, Sergio Ciordia, María C. Mena, Elvira Arza, Manuel R. Ramírez |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2018-01-01
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Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2018/3183794 |
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