Young and Especially Senescent Endothelial Microvesicles Produce NADPH: The Fuel for Their Antioxidant Machinery

In a previous study, we demonstrated that endothelial microvesicles (eMVs) have a well-developed enzymatic team involved in reactive oxygen species detoxification. In the present paper, we demonstrate that eMVs can synthesize the reducing power (NAD(P)H) that nourishes this enzymatic team, especiall...

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Bibliographic Details
Main Authors: Guillermo Bodega, Matilde Alique, Lourdes Bohórquez, Miriam Morán, Luis Magro, Lilian Puebla, Sergio Ciordia, María C. Mena, Elvira Arza, Manuel R. Ramírez
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/3183794