Impact of fatty acid binding protein 5-deficiency on COPD exacerbations and cigarette smoke-induced inflammatory response to bacterial infection

Abstract Background Although cigarette smoking (CS) is by far the most important risk factor of chronic obstructive pulmonary disease (COPD), repeated and sustained infections are clearly linked to disease pathogenesis and are responsible for acute inflammatory flares (i.e. COPD exacerbations). We h...

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Bibliographic Details
Main Authors: Deviyani M. Rao, Della T. Phan, Michelle J. Choo, Michael R. Weaver, Rebecca E. Oberley-Deegan, Russell P. Bowler, Fabienne Gally
Format: Article
Language:English
Published: Wiley 2019-03-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40169-019-0227-8