NmFGF1-Regulated Glucolipid Metabolism and Angiogenesis Improves Functional Recovery in a Mouse Model of Diabetic Stroke and Acts via the AMPK Signaling Pathway

NmFGF1-Regulated Glucolipid Metabolism and Angiogenesis Improves Functional Recovery in a Mouse Model of Diabetic Stroke and Acts via the AMPK Signaling Pathway

Diabetes increases the risk of stroke, exacerbates neurological deficits, and increases mortality. Non-mitogenic fibroblast growth factor 1 (nmFGF1) is a powerful neuroprotective factor that is also regarded as a metabolic regulator. The present study aimed to investigate the effect of nmFGF1 on the...

Full description

Bibliographic Details
Main Authors: Yeli Zhao, Shasha Ye, Jingjing Lin, Fei Liang, Jun Chen, Jian Hu, Kun Chen, Yani Fang, Xiongjian Chen, Ye Xiong, Li Lin, Xianxi Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
ischemic stroke
diabetes
nmFGF1
angiogenesis
AMPK
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.680351/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.680351/full

Similar Items