Chromatin compaction protects genomic DNA from radiation damage.

Genomic DNA is organized three-dimensionally in the nucleus, and is thought to form compact chromatin domains. Although chromatin compaction is known to be essential for mitosis, whether it confers other advantages, particularly in interphase cells, remains unknown. Here, we report that chromatin co...

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Bibliographic Details
Main Authors: Hideaki Takata, Tomo Hanafusa, Toshiaki Mori, Mari Shimura, Yutaka Iida, Kenichi Ishikawa, Kenichi Yoshikawa, Yuko Yoshikawa, Kazuhiro Maeshima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3794047?pdf=render