Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein

<p>Abstract</p> <p>Background</p> <p>Mechanisms by which HIV-1 mediates reductions in CD4+ cell levels in infected persons are being intensely investigated, and have broad implications for AIDS drug and vaccine development. Virally induced changes in membrane ionic perm...

Full description

Bibliographic Details
Main Authors: Garry Robert F, Rausch Joshua M, Costin Joshua M, Wimley William C
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/4/1/123