Grape polyphenols reduce gut-localized reactive oxygen species associated with the development of metabolic syndrome in mice.

High-fat diet (HFD)-induced leaky gut syndrome combined with low-grade inflammation increase reactive oxygen species (ROS) in the intestine and may contribute to dysbiosis and metabolic syndrome (MetS). Poorly bioavailable and only partially metabolizable dietary polyphenols, such as proanthocyanidi...

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Bibliographic Details
Main Authors: Peter Kuhn, Hetalben M Kalariya, Alexander Poulev, David M Ribnicky, Asha Jaja-Chimedza, Diana E Roopchand, Ilya Raskin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6181265?pdf=render