Theaflavin-3,3′-Digallate Suppresses Biofilm Formation, Acid Production, and Acid Tolerance in Streptococcus mutans by Targeting Virulence Factors

Theaflavin-3,3′-Digallate Suppresses Biofilm Formation, Acid Production, and Acid Tolerance in Streptococcus mutans by Targeting Virulence Factors

As one of the most important cariogenic pathogens, Streptococcus mutans has strong abilities to form biofilms, produce acid and tolerate acid. In present study, we found that theaflavin-3,3′-digallate (TF3) had an inhibitory effect on S. mutans UA159 in vitro. Visualized by field emission-scanning e...

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Bibliographic Details
Main Authors: Sa Wang, Yuan Wang, Ying Wang, Zhuhui Duan, Zongxin Ling, Wenzhi Wu, Suman Tong, Huiming Wang, Shuli Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus mutans
theaflavin-3
3′-digallate
biofilms
extracellular polymeric substances
extracellular DNA
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01705/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01705/full

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