SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury

SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury

Summary: Hepatic stellate cells (HSCs) are crucial for liver injury repair and cirrhosis. However, the mechanism of chemotactic recruitment of HSCs into injury loci is still largely unknown. Here, we demonstrate that serum amyloid A1 (SAA1) acts as a chemokine recruiting HSCs toward injury loci sign...

Full description

Bibliographic Details
Main Authors: Anteneh Getachew, Nasir Abbas, Kai You, Zhen Yang, Muzammal Hussain, Xinping Huang, Ziqi Cheng, Shenglin Tan, Jiawang Tao, Xiaorui Yu, Yan Chen, Fan Yang, Tingcai Pan, Yingying Xu, Guosheng Xu, Yuanqi Zhuang, FeiMa Wu, Yinxiong Li
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Biochemistry
Cell engineering
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100451X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422100451X

Similar Items