The Base Excision Repair system of Salmonella enterica serovar typhimurium counteracts DNA damage by host nitric oxide.

The Base Excision Repair system of Salmonella enterica serovar typhimurium counteracts DNA damage by host nitric oxide.

Intracellular pathogens must withstand nitric oxide (NO.) generated by host phagocytes. Salmonella enterica serovar Typhimurium interferes with intracellular trafficking of inducible nitric oxide synthase (iNOS) and possesses multiple systems to detoxify NO.. Consequently, the level of NO. stress en...

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Bibliographic Details
Main Authors: Anthony R Richardson, Khanh C Soliven, Margaret E Castor, Penelope D Barnes, Stephen J Libby, Ferric C Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2680585?pdf=render

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http://europepmc.org/articles/PMC2680585?pdf=render

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