Leishmanicidal activity of Piper nigrum bioactive fractions is interceded via apoptosis in vitro and substantiated by Th1 immunostimulatory potential in vivo

Leishmanicidal activity of Piper nigrum bioactive fractions is interceded via apoptosis in vitro and substantiated by Th1 immunostimulatory potential in vivo

VL is a life-threatening protozoal infection chiefly impinging the rural and poor population in the tropical and sub-tropical countries. The deadly affliction is rapidly expanding after its association with AIDS, swiftly defying its status of a neglected disease. Despite successful formulation of va...

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Bibliographic Details
Main Authors: Garima eChouhan, Mohammad eIslamuddin, Muzamil Yaqub Want, Hani A Ozbak, Hassan A Hemeg, DINKAR eSAHAL, Farhat eAfrin
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Microbiology
Subjects:
Apoptosis
Leishmania donovani
Piper nigrum
Visceral leishmaniasis
immunomodulatory
antileishmanial
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01368/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01368/full

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