L1cam is crucial for cell locomotion and terminal translocation of the Soma in radial migration during murine corticogenesis.

L1cam (L1) is a cell adhesion molecule associated with a spectrum of human neurological diseases, the most well-known being X-linked hydrocephalus. Although we recently demonstrated that L1 plays an important role in neuronal migration during cortical histogenesis, the mechanisms of delayed migratio...

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Bibliographic Details
Main Authors: Madoka Tonosaki, Kyoko Itoh, Masafumi Umekage, Tomokazu Kishimoto, Takeshi Yaoi, Vance P Lemmon, Shinji Fushiki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3904877?pdf=render