SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

Abstract Background Cancer genomes are peppered with somatic mutations imprinted by different mutational processes. The mutational pattern of a cancer genome can be used to identify and understand the etiology of the underlying mutational processes. A plethora of prior research has focused on examin...

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Bibliographic Details
Main Authors: Erik N. Bergstrom, Mi Ni Huang, Uma Mahto, Mark Barnes, Michael R. Stratton, Steven G. Rozen, Ludmil B. Alexandrov
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Genomics
Subjects:
Somatic mutations
Mutational patterns
Mutational signatures
Online Access:http://link.springer.com/article/10.1186/s12864-019-6041-2

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