Altered resting state cortico-striatal connectivity in mild to moderate stage Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder that is characterized by dopamine depletion in the striatum. One consistent pathophysiological hallmark of PD is an increase in spontaneous oscillatory activity in the basal ganglia thalamocortical networks. We evaluated these effe...

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Bibliographic Details
Main Authors: Youngbin Kwak, Scott Peltier, Nicolaas Bohnen, Martijn Müller, Praveen Dayalu, Rachael D Seidler
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-09-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2010.00143/full