(–)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1

(–)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1

Abstract (–)-Epigallocatechin-3-gallate (EGCG), the major active polyphenol extracted from green tea, has been shown to induce apoptosis and inhibit cell proliferation, cell invasion, angiogenesis and metastasis. Herein, we evaluated the in vivo effects of EGCG in acute myeloid leukaemia (AML) using...

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Bibliographic Details
Main Authors: Fernanda Isabel Della Via, Rodrigo Naoto Shiraishi, Irene Santos, Karla Priscila Ferro, Myriam Janeth Salazar-Terreros, Gilberto Carlos Franchi Junior, Eduardo Magalhães Rego, Sara Teresinha Olalla Saad, Cristiane Okuda Torello
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88478-z

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https://doi.org/10.1038/s41598-021-88478-z

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