Minimal residual disease-based risk stratification in Chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction.

Minimal residual disease, or MRD, is an important prognostic indicator in childhood acute lymphoblastic leukemia. In ALL-IC-BFM 2002 study, we employed a standardized method of flow cytometry MRD monitoring for multiple centers internationally using uniformed gating, and determined the relevant MRD-...

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Bibliographic Details
Main Authors: Suk Hang Cheng, Kin Mang Lau, Chi Kong Li, Natalie P H Chan, Rosalina K L Ip, Chi Keung Cheng, Vincent Lee, Matthew M K Shing, Alex W K Leung, Shau Yin Ha, Daniel K L Cheuk, Anselm C W Lee, Chak Ho Li, Chung Wing Luk, Siu Cheung Ling, Ondrej Hrusak, Ester Mejstrikova, Yonna Leung, Margaret H L Ng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3723913?pdf=render