Apolipoprotein E Induced Cognitive Dysfunction: Mediation Analysis of Lipids and Glucose Biomarkers in an Elderly Cohort Study

Apolipoprotein E Induced Cognitive Dysfunction: Mediation Analysis of Lipids and Glucose Biomarkers in an Elderly Cohort Study

IntroductionPrior evidence suggested Apolipoprotein E (APOE), lipids, and glucose metabolism may act through the same pathways on the pathogenesis of Alzheimer’s disease (AD).MethodsThis prospective study used data from the Chinese Longitudinal Healthy Longevity Study. We tested the associations of...

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Bibliographic Details
Main Authors: Linxin Liu, Huichu Li, Hari Iyer, Andy J. Liu, Yi Zeng, John S. Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
APOE
lipids
glucose
cognitive function
mediation analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.727289/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.727289/full

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