Tissue specificity of DNA damage response and tumorigenesis
The genome of cells is constantly challenged by DNA damages from endogenous metabolism and environmental agents. These damages could potentially lead to genomic instability and thus to tumorigenesis. To cope with the threats, cells have evolved an intricate network, namely DNA damage response (DDR)...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
China Anti-Cancer Association
2019-09-01
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| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/1443 |