Engineered Bovine Antibodies in the Development of Novel Therapeutics, Immunomodulators and Vaccines
Some bovine antibodies across all classes are unique, such as the CDR3 of the variable heavy-domain (VH CDR3), which is exceptionally long (up to 66 amino acids), unlike most conventional antibodies where the VH CDR3 loops range from 10 to 25 amino acids. The exceptionally long VH CDR3 is encoded by...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-05-01
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Series: | Antibodies |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4468/3/2/205 |