Engineered Bovine Antibodies in the Development of Novel Therapeutics, Immunomodulators and Vaccines

Some bovine antibodies across all classes are unique, such as the CDR3 of the variable heavy-domain (VH CDR3), which is exceptionally long (up to 66 amino acids), unlike most conventional antibodies where the VH CDR3 loops range from 10 to 25 amino acids. The exceptionally long VH CDR3 is encoded by...

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Bibliographic Details
Main Authors: Madhuri Koti, Surinder S. Saini, Ashish Sachan, Azad K. Kaushik
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/3/2/205