HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis.
Epigenetic mechanisms regulate the expression of virulence traits in diverse pathogens, including protozoan and fungi. In the human fungal pathogen Candida albicans, virulence traits such as antifungal resistance, white-opaque switching, and adhesion to lung cells are regulated by histone deacetylas...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-08-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2921335?pdf=render |