Neutral lipids as early biomarkers of cellular fate: the case of α-synuclein overexpression

Abstract α-synuclein (α-syn) accumulation and aggregation is a common pathological factor found in synucleinopathies, a group of neurodegenerative disorders that includes Parkinson´s disease (PD). It has been proposed that lipid dyshomeostasis is responsible for the occurrence of PD-related processe...

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Bibliographic Details
Main Authors: Natalia P. Alza, Melisa A. Conde, Paola G. Scodelaro-Bilbao, Gabriela A. Salvador
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03254-7