In Vitro Properties and Virulence of Contemporary Recombinant Influenza B Viruses Harboring Mutations of Cross-Resistance to Neuraminidase Inhibitors

In Vitro Properties and Virulence of Contemporary Recombinant Influenza B Viruses Harboring Mutations of Cross-Resistance to Neuraminidase Inhibitors

Three neuraminidase inhibitors (NAIs: Oseltamivir, zanamivir and peramivir) are currently approved in many countries for the treatment of influenza A and B infections. The emergence of influenza B viruses (IBVs) containing mutations of cross-resistance to these NAIs constitutes a serious clinical th...

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Bibliographic Details
Main Authors: Clément Fage, Yacine Abed, Liva Checkmahomed, Marie-Christine Venable, Guy Boivin
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Viruses
Subjects:
influenza B
resistance
fitness
mouse model and neuraminidase mutation
Online Access:http://www.mdpi.com/1999-4915/11/1/6

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http://www.mdpi.com/1999-4915/11/1/6

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