Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals.

Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals.

Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site (CD4bs antibodies), can protect from infection by HIV-1, and their elicitation may be an interesting goal for any vaccination strategy. To identi...

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Bibliographic Details
Main Authors: Jorge Carrillo, Luis Manuel Molinos-Albert, Maria Luisa Rodríguez de la Concepción, Silvia Marfil, Elisabet García, Ronald Derking, Rogier W Sanders, Bonaventura Clotet, Julià Blanco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4372395?pdf=render

Internet

http://europepmc.org/articles/PMC4372395?pdf=render

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