Differential anatomical expression of ganglioside GM1 species containing d18:1 or d20:1 sphingosine detected by MALDI Imaging Mass Spectrometry in mature rat brain

GM1 ganglioside plays a role in essential neuronal processes, including differentiation, survival and signaling. Yet, little is known about GM1 species with different sphingosine bases, such as the most abundant species containing 18 carbon atoms in the sphingosine chain (GM1d18:1), and the less abu...

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Bibliographic Details
Main Authors: Nina eWeishaupt, Sarah eCaughlin, Ken KKC Yeung, Shawn N Whitehead
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Neuroanatomy
Subjects:
GM1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2015.00155/full