Structural MRI at 7T reveals amygdala nuclei and hippocampal subfield volumetric association with Major Depressive Disorder symptom severity

Abstract Subcortical volumetric changes in major depressive disorder (MDD) have been purported to underlie depressive symptomology, however, the evidence to date remains inconsistent. Here, we investigated limbic volumes in MDD, utilizing high-resolution structural images to allow segmentation of th...

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Bibliographic Details
Main Authors: S. S. G. Brown, J. W. Rutland, G. Verma, R. E. Feldman, J. Alper, M. Schneider, B. N. Delman, J. M. Murrough, P. Balchandani
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-46687-7