Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21

Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21

Activation of pancreatic stellate cells (PSCs) initiates pancreatic fibrosis in chronic pancreatitis and furnishes a niche that enhances the malignancy of pancreatic cancer cells (PCCs) in pancreatic ductal adenocarcinoma (PDAC). Resveratrol (RSV), a natural polyphenol, exhibits potent antioxidant a...

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Bibliographic Details
Main Authors: Bin Yan, Liang Cheng, Zhengdong Jiang, Ke Chen, Cancan Zhou, Liankang Sun, Junyu Cao, Weikun Qian, Jie Li, Tao Shan, Jianjun Lei, Qingyong Ma, Jiguang Ma
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/1346958

Internet

http://dx.doi.org/10.1155/2018/1346958

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