The stochastic behavior of a molecular switching circuit with feedback

<p>Abstract</p> <p>Background</p> <p>Using a statistical physics approach, we study the stochastic switching behavior of a model circuit of multisite phosphorylation and dephosphorylation with feedback. The circuit consists of a kinase and phosphatase acting on multiple...

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Bibliographic Details
Main Authors: Smith Eric, Krishnamurthy Supriya, Krakauer David, Fontana Walter
Format: Article
Language:English
Published: BMC 2007-05-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/2/1/13