Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation

Lipid metabolism in visceral fat cells is correlated with metabolic syndrome and cardiovascular diseases. Okadaic-acid, a 38-carbon fatty acid isolated from the black sponge Halichondria okadai, can stimulate lipolysis by promoting the phosphorylation of several proteins in adipocytes. However, the...

Full description

Bibliographic Details
Main Authors: Nen-Chung Chang, Aming Chor-Ming Lin, Cheng-Chen Hsu, Jung-Sheng Liu, Leo Tsui, Chien-Yuan Chen, Thanasekaran Jayakumar, Tsorng-Harn Fong
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/545739