Inhibition of <i>C. albicans</i> Dimorphic Switch by Cobalt(II) Complexes with Ligands Derived from Pyrazoles and Dinitrobenzoate: Synthesis, Characterization and Biological Activity

Inhibition of <i>C. albicans</i> Dimorphic Switch by Cobalt(II) Complexes with Ligands Derived from Pyrazoles and Dinitrobenzoate: Synthesis, Characterization and Biological Activity

Seven cobalt(II) complexes of pyrazole derivatives and dinitrobenzoate ligands were synthesized and characterized. The single-crystal X-ray diffraction structure was determined for one of the ligands and one of the complexes. The analysis and spectral data showed that all the cobalt complexes had oc...

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Bibliographic Details
Main Authors: Daniela Fonseca, Sandra M. Leal-Pinto, Martha V. Roa-Cordero, José D. Vargas, Erika M. Moreno-Moreno, Mario A. Macías, Leopoldo Suescun, Álvaro Muñoz-Castro, John J. Hurtado
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
pyrazole and dinitrobenzoate ligands
cobalt(II) complexes
crystal structure
<i>Trypanosoma cruzi</i>
antifungal activity
cytotoxicity
dimorphic switch
Online Access:https://www.mdpi.com/1422-0067/20/13/3237

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https://www.mdpi.com/1422-0067/20/13/3237

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