Establishment of the circadian metabolic phenotype strategy in spontaneously hypertensive rats: a dynamic metabolomics study

Abstract Background Circadian rhythms play a fundamental role in the progression of cardiovascular events. Almost all cardiovascular diseases have a circadian misalignment usually characterized by changes in metabolites. This study aimed to dynamically monitor rhythmic biomarkers, to elucidate the m...

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Bibliographic Details
Main Authors: Huanjun Wang, Xiaoming Wang, Dongmei Qi, Mengjia Sun, Qingqing Hou, Yunlun Li, Haiqiang Jiang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-020-02222-1