UPLC-Q-TOF/MS-Based Serum and Urine Metabonomics Study on the Ameliorative Effects of Palmatine on Helicobacter pylori–Induced Chronic Atrophic Gastritis

UPLC-Q-TOF/MS-Based Serum and Urine Metabonomics Study on the Ameliorative Effects of Palmatine on Helicobacter pylori–Induced Chronic Atrophic Gastritis

ObjectiveThe main objective of this study was to investigate the ameliorative effects of Palmatine (Pal) on Helicobacter pylori (H. pylori) induced chronic atrophic gastritis (CAG)MethodBody function, serum biochemical indicators and histopathology were used to evaluate the pharmacodynamics of Pal o...

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Bibliographic Details
Main Authors: Xing Chen, Jianzhong Zhang, Ruilin Wang, Honghong Liu, Chunmei Bao, Shihua Wu, Jianxia Wen, Tao Yang, Ying Wei, Sichen Ren, Yuling Tong, Yanling Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
palmatine
Helicobacter pylori
chronic atrophic gastritis
metabolomics
molecular mechanisms
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.586954/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.586954/full

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