Systematic identification of non-canonical transcription factor motifs

Abstract Sequence-specific transcription factors (TFs) recognize motifs of related nucleotide sequences at their DNA binding sites. Upon binding at these sites, TFs regulate critical molecular processes such as gene expression. It is widely assumed that a TF recognizes a single “canonical” motif, al...

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Bibliographic Details
Main Authors: Luis Chumpitaz-Diaz, Md. Abul Hassan Samee, Katherine S. Pollard
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Molecular and Cell Biology
Online Access:https://doi.org/10.1186/s12860-021-00382-6