Phase I Study of Oral Vinorelbine in Combination with Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Using Two Different Schedules.

Phase I Study of Oral Vinorelbine in Combination with Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Using Two Different Schedules.

PURPOSE:This study aimed to evaluate the safety, tolerability and pharmacokinetics of the combination of oral vinorelbine with erlotinib using the conventional (CSV) and metronomic (MSV) dosing schedules in patients with advanced non-small cell lung cancer (NSCLC). METHODS:This was an open-label, mu...

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Bibliographic Details
Main Authors: Natalia Sutiman, Zhenxian Zhang, Eng Huat Tan, Mei Kim Ang, Shao-Weng Daniel Tan, Chee Keong Toh, Quan Sing Ng, Balram Chowbay, Wan-Teck Lim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4852941?pdf=render

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http://europepmc.org/articles/PMC4852941?pdf=render

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