A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections.

Organisms evolve two routes to surviving infections-they can resist pathogen growth (resistance) and they can endure the pathogenesis of infection (tolerance). The sum of these two properties together defines the defensive capabilities of the host. Typically, studies of animal defenses focus on eith...

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Bibliographic Details
Main Authors: Janelle S Ayres, David S Schneider
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2596860?pdf=render