MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells

Oxidative stress predisposes to several aging-associated diseases, such as cardiovascular diseases and cancer. In aging, increase in the production of reactive oxygen species is typically accompanied with a decline in adaptive stress responses to oxidative stress. The decline is primarily due to a d...

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Bibliographic Details
Main Authors: Suvi M. Kuosmanen, Virve Sihvola, Emilia Kansanen, Minna U. Kaikkonen, Anna-Liisa Levonen
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718303902