A differential DNA methylome signature of pulmonary immune cells from individuals converting to latent tuberculosis infection

Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis, spreads via aerosols and the first encounter with the immune system is with the pulmonary-resident immune cells. The role of epigenetic regulations in the immune cells is emerging and we have previously shown that macrophages capacity...

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Bibliographic Details
Main Authors: Lovisa Karlsson, Jyotirmoy Das, Moa Nilsson, Amanda Tyrén, Isabelle Pehrson, Nina Idh, Shumaila Sayyab, Jakob Paues, Cesar Ugarte-Gil, Melissa Méndez-Aranda, Maria Lerm
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98542-3