Dynamic integration of enteric neural stem cells in ex vivo organotypic colon cultures

Abstract Enteric neural stem cells (ENSC) have been identified as a possible treatment for enteric neuropathies. After in vivo transplantation, ENSC and their derivatives have been shown to engraft within colonic tissue, migrate and populate endogenous ganglia, and functionally integrate with the en...

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Bibliographic Details
Main Authors: Georgina Navoly, Conor J. McCann
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95434-4