BMP-7/Smad expression in dedifferentiated Schwann cells during axonal regeneration and upregulation of endogenous BMP-7 following administration of PTH (1-34)

Purpose: To determine the expression and distribution of bone morphogenetic protein (BMP)-7 and related molecules during peripheral nerve regeneration and to assess whether administration of parathyroid hormone (PTH) drug (1-34) potentiates the intrinsic upregulation of BMP-7/Smad signaling. Methods...

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Bibliographic Details
Main Authors: Naoki Kokubu, Masaya Tsujii, Koji Akeda, Takahiro Iino, Akihiro Sudo
Format: Article
Language:English
Published: SAGE Publishing 2018-11-01
Series:Journal of Orthopaedic Surgery
Online Access:https://doi.org/10.1177/2309499018812953